Chronic Autoimmune Hepatitis
Multiple autoimmune syndrome (MAS) is a condition in which patients have at least three distinct autoimmune conditions. In multiple autoimmune syndrome, patients often have at least one dermatological condition, usually vitiligo or alopecia areata. In many cases of multiple autoimmune syndrome reported in the medical literature, vitiligo is the first autoimmune disease to be diagnosed. In these cases, vitiligo is usually bilateral and symmetrical (occurring in the same places on both sides of the body), and in most cases of vitiligo that occurred in multiple autoimmune syndrome, autoimmune thyroid disease was also present.
Researchers note that in many cases, the presence of one autoimmune disorder helps lead to the discovery of other autoimmune conditions. For instance, in an article from the Ocular Immunology and Uveitis Foundation, a patient is reported as having ocular cicatricial pemphigoid disorder in both eyes, a history of hypothyroidisim, and difficulty in swallowing. Although studies of her esophagus were non-diagnostic, additional tests showed the presence of lichen planus of the mouth. Had the patient not had evidence of autoimmune disorders, her diagnosis and subsequent treatment for lichen planus may have been missed.
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